Fundação para a Ciência e Tecnologia

Science and Technology Policy and Innovation Analysis to Maximize the Economic, Environmental and Social Benefits of Deep Sea Exploration and Oil and Gas Development in the South Atlantic Region

The ultimate goal of the +Atlantic project is to promote a consortium in the form of an International Observatory, to stimulate participatory risk governance activities, to support the design of public policies and the sustainable development of industry, so as to foster the endogenous development of Atlantic regions. It is particularly aimed to help to [...]

MR Fingerprinting for Quantitative Diffusion Imaging of the Brain

The aim of this project is to use pattern-matching strategies, based on MR Fingerprinting for estimating the water diffusion coefficient in the brain. Since diffusion-weighted sequences are typically also T2-weighted, and given that the latter are much less sensitive to patient motion, we have started by estimating T2, using Multi-Echo Spin Echo acquisitions. We have [...]

Development of a low field MRI scanner for stroke imaging

Diffusion-weighted imaging is widely used in the clinic to detect stroke lesions due to its high sensitivity to microstructural tissue changes. The aim of this project is to develop a low field MR equipment (10mT) for stroke imaging. Our role is to develop diffusion pulse sequences accounting for the hardware limitations of the developed system, [...]

Robotics, Brain and Cognition Lab

The Robotics, Brain and Cognition Lab (RBCogLab) is part of the Portuguese Roadmap of Research Infrastructures. RBCog-Lab supports an integrated multidisciplinary research endeavour (neuroscience, developmental psychology, cognitive science, psychophysics, machine learning and other engineering subjects) not only promoting novel robotic methodologies, but also contributing to a better understanding of the human brain. To be effective [...]

Sensing dysfunctional E-cadherin cells in gastric epithelia

E-Cadherin is a key molecule for adhesion between cells, being a fundamental protein regulating normal epithelia architecture and homeostasis. E-cadherin loss of expression and/or function, occurring in more than 70% of all carcinomas, leads to increasedinvasion which is a hallmark of cancer cells. However, the molecular and cellular mechanisms by which cells with dysfunctional E-cadherin [...]

Sparse Modeling and Estimation of Motion Fields

In this project we will explore the use of sparse techniques to improve the estimation of multiple motion fields as well as spacevarying switching matrix (stochastic matrix) that describes the switching process associated to the movement of each target. As scientific outcomes of the project, we expect to obtain reliable estimates for the model parameters [...]

Tracing Gastric Cancer using Quantitative Bioimaging Analysis

Currently, diagnosis and therapy strategies for cancer patients strongly relies on cell- or tissue-based visual assessment of tumor markers. However, in most clinical, pathology and research centers the criteria used for their visual classification is merely qualitative and thus strongly operator-dependent. An inaccurate biomarker evaluation can be as harmful as an inappropriate drug choice in [...]

Load transportation using Unmanned Aerial Vehicles

Unmanned aerial vehicles (UAVs) are rapidly evolving to become highly capable sensing platforms that can navigate and track trajectories with great precision. The goal of this project is to address new challenges in motion control of UAVs that involve interaction with the environment. This is currently a great focus of interest as evidenced by several [...]

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